Maciej Antczak

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Research

Qrorcid
  • » Grants
  • » International cooperation
  • » RNAQuANet
  • » RNAhugs
  • » WebTetrado
  • » RNAsolo
  • » RNArefiner
  • » RNAspider
  • » RNAloops
  • » RNAtive
  • » RNA-Puzzles Toolkit
  • » RNAfitme
  • » RNAvista
  • » rnaqua
  • » descs-standalone
  • » RNApolis
  • » RNAssess
  • » RNApdbee 2.0
  • » RNAComposer
  • » RNAlyzer
  • » SphereGrinder

Grants

I run, co-ordinated and/or participated in the following grants:

  • » 2025-2028 - Modelowanie struktury RNA ukierunkowane na motywy funkcjonalne (Functional motif-targeted RNA structure modeling)
    [NCN OPUS – 2024/53/B/ST6/02789] - executor.
  • » 2023 - 2025 - SpacE Data bRokEriNg optImizaTion sYstem.
    [POLLUX-XI/15/Serenity/2023] - work package leader.
  • » 2022 - 2027 - Opracowanie uniwersalnej platformy szybkiego reagowania, opartej na technologii RNA, zapewniającej krajowe bezpieczeństwo lekowe i epidemiologiczne. (Development of a universal fast-response platform, based on RNA technology, ensuring the national drug and epidemiological safety)
    [ABM – 2021/ABM/05/00004-00] - area expert.
  • » 2021-2023 - ECBiG – Europejskie Centrum Bioinformatyki i Genomiki – MOSAIC. (ECBG - European Centre for Bioinformatics and Genomics – MOSAIC)
    [POIR.04.02.00-00-D017/20] - executor.
  • » 2020-2023 - Eksploracja cech i modelowanie struktury kwadrupleksów. (Feature exploration and modelling of quadruplex structures)
    [NCN OPUS – 2019/35/B/ST6/03074] - executor.
  • » 2019-2020 - Agenda Badawcza w zakresie modeli predykcji produkcji i zapotrzebowania na energię dla Kogeneracja Zachód S.A. Poznań. (Research Agenda in the field of prediction models of production and energy demand for Kogeneracja Zachód S.A. Poznan) - data scientist.
  • » 2019 - Zastosowanie metod uczenia maszynowego do optymalizacji procesów planowania sprzedaży i operacji dla produktów koncernu Beiersdorf AG. (Application of machine learning methods for optimization of sales planning and operations processes for Beiersdorf AG products) - research consultant.
  • » 2018-2020 - ECBiG – Europejskie Centrum Bioinformatyki i Genomiki. (ECBG - European Centre for Bioinformatics and Genomics)
    [POIR.04.02.00-30-A004/16] - executor.
  • » 2017-2020 - RNApolis – metody i algorytmy do modelowania i analizy struktury RNA. (RNApolis - methods and algorithms to model and analyze the RNA structure) [NCN OPUS – 2016/23/B/ST6/03931] - executor.
  • » 2017-2019 - Struktura RNA i jego oddziaływania z białkiem Gag warunkujące funkcje RNA Ty1 na różnych etapach replikacji retrotranspozonu. (RNA structures and interactions with Gag protein that specify Ty1 RNA functions during retrotransposon replication)
    [NCN SONATA BIS – 2016/22/E/NZ3/00426] - executor.
  • » 2017-2018 - Opracowanie systemu automatyki budynkowej używającego systemów rozpoznawania obrazu oraz metod głębokiego uczenia do identyfikacji zagrożeń, poprawy bezpieczeństwa użytkownika i sterowania elementami wykonawczymi. (Development of building automation system integrating image recognition and deep learning methods to identify threats, improve a user safety, and control executive elements)
    [NCBR – POIR.01.11.17-00-0713/17] - R&D manager.
  • » 2015-2017 - Optilion – platforma do ciągłej ewaluacji algorytmów optymalizacyjnych. (Optilion - continuous evaluation platform for optimization algorithms) [NCBR – LIDER V] - member of the research team.
  • » 2013-2016 - Informatyczne modele i metody w biologii komórkowej. (Computational models and methods in cell biology)
    [NCN OPUS - 2012/05/B/ST6/03026] - executor.
  • » 2013-2016 - Automatyczne, wysokoprzepustowe modelowanie struktur przestrzennych RNA. Integrowanie informatyki z eksperymentem biochemicznym. (Automated, high-throughput modeling of RNA three-dimensional structures. Linking informatics and biochemical experiment)
    [NCN MAESTRO - 2012/06/A/ST6/00384] - executor.
  • » 2013-2014 - Opracowanie i implementacja metody obliczeniowej pozwalającej na przewidywanie konformacji przestrzennych zasad azotowych na podstawie łańcucha głównego cząsteczki RNA. (Design and development of computational method that allows to predict base pair coordinates based on backbone 3D structure of RNAs) [91-555/13MK] - principal investigator and manager of project for young researchers.
  • » 2010-2012 - Rozwój Infrastruktury Europejskiego Centrum Bioinformatyki i Genomiki. (A development of the European Center of Bioinformatics and Genomics infrastructure) [POIG.02.02-30-009/09] - administrative specialist.
  • » 2008-2011 - Pierwszorzędowa i przestrzenna struktura kwasów nukleinowych i białek - analiza i algorytmy. (Primary and tertiary structure of nucleic acids and proteins - analysis and algorithms) [NN519314635] - executor.

 

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International cooperation

 

  • » 2009, August – Visiting researcher, Protein Structure Prediction Center, State California University in Davis, USA. Collaborative research in the field of modeling and evaluation of protein tertiary structures. Responsible for design and implementation of a novel computational approaches.
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RNAQuANet

RNAQuANet

RNAQuANet is a web server for a general quality assessment on 3D RNA structures.

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RNAhugs

RNAhugs

RNAhugs is a web server for user-customized flexible alignment of 3D RNA structures.

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WebTetrado

WebTetrado

WebTetrado is a computational server for identification and classification of tetrads and quadruplexes.

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RNAsolo

RNAsolo

RNAsolo is a repository of PDB-derived RNA 3D structures.

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RNArefiner

RNArefiner

RNArefiner is a computational server for refinement of stereochemical properties of RNA 3D structures.

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RNAspider

RNAspider

RNAspider is a webserver to analyze entanglements in RNA 3D structures.

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RNAloops

RNAloops

RNAloops is a database of n-way junctions identified in PDB-deposited RNA 3D structures.

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RNAtive

RNAtive

RNAtive is a tool for reference-free ranking of RNA 3D structure models.

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RNA-Puzzles Toolkit

RNA-Puzzles Toolkit is a computational resource of RNA 3D structure benchmark datasets, assessment metrics and structure manipulation tools.

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RNAfitme

RNAfitme

RNAfitme is a webserver to reconstruct full-atomic RNA 3D structure based on sequence and fixed sugar-phopshate backbone, remodel the 3D structure, and reduce steric clashes.

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RNAvista

RNAvista

RNAvista is a webserver to assess RNA secondary structure with non-canonical base pairs based on user-provided sequence or secondary structure containing canonical base pairs only.

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rnaqua

RNA QUality Assessment tool (RNAQUA) is RESTful web service client developed in Java providing a set of web services designed initially for RNAssess to support quality assessment of RNA 3D structures.

Tool was published in the public repository on GitHub. To play with it please download its binary and a set of proposed use cases included in the archive provided here.

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descs-standalone

A tool for identification and structural comparison of a local, contacts-based structural motives, called descriptors. The descriptors can be built on unmodified residues of the following biological molecules, namely proteins and RNAs. Both PDB and CIF formats are supported.

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RNApolis

RNApolis

RNApolis is a flagship of RNA bioinformatics group carrying out the research in ECBiG. This portal collects the most important information about computational tools dedicated to RNA analysis developed by the group, and allows to enter them directly from one place.

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RNAssess

RNAssess

RNAssess is a novel webserver dedicated to visual evaluation of RNA 3D models in the context of known reference structure for a wide range of accuracy levels (from atomic to the whole molecule perspective).

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RNApdbee 2.0

RNApdbee2.0

RNApdbee 2.0 is a webserver that allows to annotate secondary structures of knotted and unknotted RNAs. The secondary structure of RNA, encoded in dot-bracket, BPSEQ and CT together with a graphical image, can be derived from its tertiary structure provided in pdb file or from base-pair list provided in BPSEQ or CT.

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RNAComposer

RNAComposer

The RNAComposer system offers a new user-friendly approach to the fully automated prediction of large RNA 3D structures. The method is based on the machine translation principle and operates on the RNA FRABASE database acting as the dictionary relating RNA secondary structure and tertiary structure elements.

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RNAlyzer

RNAlyzer

The RNAlyzer is a computational method for comparison of RNA 3D models with the reference structure and for discrimination between the correct and incorrect ones.

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SphereGrinder

SphereGrinder

The SphereGrinder provides the research community with a freely available and easy to use software tool for comprehensive quality inspection conducted between the set of predicted protein models and the reference structure.

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