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Projects: BS-MLP

MLP accompanied Beam Search for the Resonance Assignment Problem

Resonance signal assignment is a well known problem encountered during the process of biomolecule structure determination based on Nuclear Magnetic Resonance (NMR) spectroscopy. As one of the first steps following the experimental part of the process, it significantly affects the quality of a resulting molecule model. Here we present a new approach for automated resonance signal assignment in two-dimensional NMR spectra of RNA molecules. The proposed algorithm combines beam search with a neural network in order to reconstruct and evaluate solutions.

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